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CAS 60-80-0 Properties

MSDS  
: Phenazone
CAS  : 60-80-0
Molecular Formula  
: C11H12N2O
Molecular Weight  
: 188.095
SYNONYMS  : 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one

  
MSDS LIST:
  • MSDS Antipyrine CAS 60-80-0 MSDS * Analgesine * Anodynin * Anodynine * Antipirin * Antipyrin * Apirelina * Azophen * Azophene * 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one * Dimethyloxychinizin * Dimethyloxyquinazine * 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one * 2,3-Dimethyl-1-phenyl-5-pyrazolone * Fenazon * Fenazone * Methozin * Oxydimethylquinazine * Parodyne * Phenazon * Phenazone * Phenazonum * Phenozone * Phenazone (pharmaceutical) * 1-Phenyl-2,3-dimethylpyrazole-5-one * 1-Phenyl-2,3-dimethyl-5-pyrazolone * Phenylon * Phenylone * Pyrazophyl * 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl- * Sedatin * Sedatine
    60-80-0 SYNONYMS   : * Analgesine * Anodynin * Anodynine * Antipirin * Antipyrin * Apirelina * Azophen * Azophene * 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one * Dimethyloxychinizin * Dimethyloxyquinazine * 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one * 2,3-Dimethyl-1-phenyl-5-pyrazolone * Fenazon * Fenazone * Methozin * Oxydimethylquinazine * Parodyne * Phenazon * Phenazone * Phenazonum * Phenozone * Phenazone (pharmaceutical) * 1-Phenyl-2,3-dimethylpyrazole-5-one * 1-Phenyl-2,3-dimethyl-5-pyrazolone * Phenylon * Phenylone * Pyrazophyl * 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl- * Sedatin * Sedatine *** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CD2450000 CHEMICAL NAME : Antipyrine CAS REGISTRY NUMBER : 60-80-0 LAST UPDATED : 199701 DATA ITEMS CITED : 23 MOLECULAR FORMULA : C11-H12-N2-O MOLECULAR WEIGHT : 188.25 WISWESSER LINE NOTATION : T5NNVJ A1 BR& E1 COMPOUND DESCRIPTOR : Agricultural Chemical Tumorigen Drug Mutagen Human SYNONYMS/TRADE NAMES : * Analgesine * Anodynin * Anodynine * Antipirin * Antipyrin * Apirelina * Azophen * Azophene * 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one * Dimethyloxychinizin * Dimethyloxyquinazine * 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one * 2,3-Dimethyl-1-phenyl-5-pyrazolone * Fenazon * Fenazone * Methozin * Oxydimethylquinazine * Parodyne * Phenazon * Phenazone * Phenazonum * Phenozone * Phenazone (pharmaceutical) * 1-Phenyl-2,3-dimethylpyrazole-5-one * 1-Phenyl-2,3-dimethyl-5-pyrazolone * Phenylon * Phenylone * Pyrazophyl * 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl- * Sedatin * Sedatine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - man DOSE/DURATION : 74 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1705 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,401,1959 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1570 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Cardiac - other changes Nutritional and Gross Metabolic - body temperature decrease REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 186,195,1937 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1310 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,137,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 135,376,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose v...
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  • MSDS PAGE: MSDS 60-80-0 CAS Phenazone Antipyrine; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Antipyrine
    60-80-0 SYNONYMS : Antipyrine; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Antipyrine **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 60-80-0 |Phenazone | 100.0 | 200-486-6 | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: XN Risk Phrases: 22 36/37/38 43 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. Potential Health Effects Eye: Dust may cause mechanical irritation. Skin: May cause mild skin irritation. Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Inhalation: Causes respiratory tract irritation. Chronic: No information found. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Notes to Physician: **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. **** SECTION 7 - HANDLING and STORAGE **** Handling: Use with adequate ventilation. Minimize dust generation and accumulation. Avoid prolonged or repeated contact with skin. Storage: Keep container closed when not in use. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 60-80-0: Personal Protective Equipment Eyes: Wear safety glasses with side shields. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 319 deg C @ 319mmhg Freezing/Melting Point: 113 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Very soluble in water. Specific Gravity/Density: Not available. Molecular Formula: C11H12N2O Molecular Weight: 188.0968 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable. Conditions to Avoid: None reported. Incompatibilities with Other Materials: No data reported. Hazardous Decomposition Products: Irritating and toxic fumes and gases. Hazardous Polymerization: Has not been reported. **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 60-80-0: CD2450000...
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  • MSDS PAGE: MSDS 60-80-0 CAS Antipyrine, 99% 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; Dimethyloxyquinazine; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; 2,3-Dimethyl-1-phenyl-5-pyrazolone; Oxydimethylquinazine; 1-Phenyl-2,3-dimethylpyrazole-5-one; 1-Phenyl-2,3-dimethyl-5-pyrazolone; 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-
    60-80-0 SYNONYMS : 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; Dimethyloxyquinazine; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; 2,3-Dimethyl-1-phenyl-5-pyrazolone; Oxydimethylquinazine; 1-Phenyl-2,3-dimethylpyrazole-5-one; 1-Phenyl-2,3-dimethyl-5-pyrazolone; 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl- **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 60-80-0 |Antipyrine | 99 | 200-486-6 | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: XN Risk Phrases: 22 36/37/38 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes, respiratory system and skin.Harmful. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May cause sensitization by skin contact. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause irritation of the mucous membranes. Chronic: No information found. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a cool, dry area away from incompatible substances. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 60-80-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 19...
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  • MSDS PAGE: CAS 60-80-0 MSDS palomar_edu---ANTIPYRINE.asp
    60-80-0 File Name : palomar_edu---ANTIPYRINE.asp PRODUCT #: A5882 NAME: ANTIPYRINE CRYSTALLINE MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98 Printed Monday, March 10, 1903 1:45PM Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp. P.O. Box 14508 1001 West St. Paul 1001 West St. Paul St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233 Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850 SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - - CATALOG #: A5882 NAME: ANTIPYRINE CRYSTALLINE SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - - CAS #: 60-80-0 MF: C11H12N2O EC NO: 200-486-6 SYNONYMS ANALGESINE * ANODYNIN * ANODYNINE * ANTIPIRIN * ANTIPYRIN * APIRELINA * AZOPHEN * AZOPHENE * 1,2-DIHYDRO-1,5-DIMETHYL-2-PHENYL-3H-PYRAZOL-3- ONE * DIMETHYLOXYCHINIZIN * DIMETHYLOXYQUINAZINE * 2,3-DIMETHYL-1- PHENYL-3-PYRAZOLIN-5-ONE * 2,3-DIMETHYL-1-PHENYL-5-PYRAZOLONE * FENAZON (CZECH) * FENAZONE * METHOZIN * OXYDIMETHYLQUINAZINE * PARODYNE * PHENAZON * PHENAZONE * PHENAZONUM * PHENOZONE * PHENAZONE (PHARMACEUTICAL) * 1-PHENYL-2,3-DIMETHYLPYRAZOLE-5-ONE * 1-PHENYL-2,3- DIMETHYL-5-PYRAZOLONE * PHENYLON * PHENYLONE * PYRAZOPHYL * 3H- PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-2-PHENYL- (9CI) * SEDATIN * SEDATINE * SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - - LABEL PRECAUTIONARY STATEMENTS HARMFUL HARMFUL IF SWALLOWED. IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. MAY CAUSE SENSITIZATION BY SKIN CONTACT. TARGET ORGAN(S): BLOOD IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. WEAR SUITABLE PROTECTIVE CLOTHING. SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - - IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE. SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - - EXTINGUISHING MEDIA WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM. SPECIAL FIREFIGHTING PROCEDURES WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. UNUSUAL FIRE AND EXPLOSIONS HAZARDS EMITS TOXIC FUMES UNDER FIRE CONDITIONS. SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - - Page 1 PRODUCT #: A5882 NAME: ANTIPYRINE CRYSTALLINE MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98 Printed Monday, March 10, 1903 1:45PM WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - - REFER TO SECTION 8. SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - - CHEMICAL SAFETY GOGGLES. COMPATIBLE CHEMICAL-RESISTANT GLOVES. NIOSH/MSHA-APPROVED RESPIRATOR. SAFETY SHOWER AND EYE BATH. MECHANICAL EXHAUST REQUIRED. AVOID INHALATION. AVOID CONTACT WITH EYES, SKIN AND CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. WASH THOROUGHLY AFTER HANDLING. HARMFUL SOLID. SENSITIZER. KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE. SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - - APPEARANCE AND ODOR WHITE CRYSTALLINE POWDER PHYSICAL PROPERTIES MELTING POINT: 111 C TO 114 C SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - - INCOMPATIBILITIES STRONG OXIDIZING AGENTS HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS TOXIC FUMES OF: CARBON MONOXIDE, CARBON DIOXIDE NITROGEN OXIDES SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - - ACUTE EFFECTS HARMFUL IF SWALLOWED. MAY BE HA...
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  • MSDS PAGE: CAS 60-80-0 MSDS ilo_org---icsc0376.asp
    60-80-0 File Name : ilo_org---icsc0376.asp ANTIPYRINE 0376 March 1996 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one CAS No: 60-80-0 2,3-Dimethyl-1-phenyl-3-pyrazolin-3-one RTECS No: CD2450000 Phenazone UN No: C11H12N2O EC No: Molecular mass: 188.2 TYPES OF ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING HAZARD/ EXPOSURE Combustible. Gives off irritating or NO open flames. Powder, water spray, foam, carbon FIRE toxic fumes (or gases) in a fire. dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! Blue lips or finger nails. Blue skin. Ventilation, local exhaust, or Fresh air, rest. Refer for medical Inhalation Shortness of breath. breathing protection. attention. Protective gloves. Skin Pain. Safety spectacles. First rinse with plenty of water for Eyes several minutes (remove contact lenses if easily possible), then take to a doctor. Blue lips or fingernails. Blue skin. Do not eat, drink, or smoke during Rinse mouth. Give a slurry of Ingestion work. activated charcoal in water to drink. Refer for medical attention. SPILLAGE DISPOSAL PACKAGING & LABELLING Sweep spilled substance into containers; if Symbol appropriate, moisten first to prevent dusting. R: Carefully collect remainder, then remove to safe S: place (extra personal protection: P2 filter respirator for harmful particles). EMERGENCY RESPONSE STORAGE Separated from strong oxidants. Prepared in the context of cooperation between the International IPCS Programme on Chemical Safety and the European Commission International 漏 IPCS 1999 Programme on Chemical Safety SEE IMPORTANT INFORMATION ON THE BACK. 0376 ANTIPYRINE IMPORTANT DATA Physical State; Appearance Routes of Exposure COLOURLESS CRYSTALS OR WHITE POWDER. The substance can be absorbed into the body by inhalation of the dust and by ingestion. Chemical Dangers Inhalation Risk The substance decomposes on heating producing toxic and corrosive fumes of nitrogen oxides. Reacts with oxidants. Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. Occupational Exposure Limits TLV not established. Effects of Short-term Exposure The substance irritates the eyes and the respiratory tract. The substance may cause effects on the blood, resulting in formation of methaemoglobin. PHYSICAL PROPERTIES Boiling point: 319C Relative density (water = 1): 1.19 Melting point: 113C Solubility in water: very good ENVIRONMENTAL DATA NOTES ADDITIONAL INFORMATION Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible LEGAL NOTICE for the use which might be made of this information 漏 IPCS 1999 ...
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  • MSDS PAGE: CAS 60-80-0 94-09-7 56-81-5 7732-18-5 MSDS bausch_com---420-01.asp
    60-80-0 94-09-7 56-81-5 7732-18-5 File Name : bausch_com---420-01.asp MATERIAL SAFETY DATA SHEET Issued: 09/07/94 Prepared by: Gary Wong Revised: 03/26/02 Manager EHS Revision: 02 Core No. 124 1. PRODUCT AND COMPANY IDENTIFICATION Antipyrine and Benzocaine Otic Solution USP Product Name: Same Generic Name: 24208-561-62 (10 ml) NDC No. Prescription only medicine, filled inside glass bottle suitable Legal Category: for dispensing, and overpacked inside a cardboard carton. Drug Composition: Local anesthetic combination BAUSCH & LOMB PHARMACEUTICALS, INC. 8500 Hidden River Parkway Tampa, FL 33637 Information: (800) 323-0000 (M-F) 8am-5pm EST Emergency: (800) 227-1427 24 hrs 2. COMPOSITION/INFORMATION ON INGREDIENTS 3 3 Description CAS # TLV (mg/m ) PEL(mg/m ) % Content Antipyrene 60-80-0 NE NE 5.4 Benzocaine 94-09-7 NE NE 1.4 Glycerin 56-81-5 NE NE >1 Purified Water 7732-18-5 NE NE >1 Ingredients 1% - Oxyquinolin Sulfate Page 1 of 6 BAUSCH & LOMB Pharmaceuticals Division MSDS: Antipyrine and Benzocaine Otic Solution USP 3. HAZARDS IDENTIFICATION ************************************************************************************************* EMERGENCY OVERVIEW Amber glass bottle in a cardboard box. Clear yellow, very viscous solution with a characteristic odor. ************************************************************************************************* POTENTIAL HEALTH HAZARDS (NTP) No No No Carcinogenicity: (IARC) (OSHA) Eye: May cause irritation to the mucous membranes and hypersensitivity. Repeated or prolonged exposure can cause conjunctivitis. Skin: May cause irritation and hypersensitivity in some individuals. Repeated or prolonged exposure can cause dermatitis. Ingestion: May cause irritation and hypersensitivity. Moderately toxic by ingestion, but large quantities may induce headache, dizziness, drowsiness, insomnia, vomiting, diarrhea, kidney failure and numbness in nose and throat. Inhalation: May cause irritation and hypersensitivity. Inhalation of vapors, given off at high temperatures, can cause defatting and irritation of the mucous membranes. Chronic Effects: 路 Antipyrene may cause methemoglobinemia (low blood oxygen levels). After repeated exposures, skin rashes can develop which may last for several weeks. 路 May cause hypersensitivity in some individuals. Target Organs: Respiratory and digestive tract and kidneys. Medical Conditions Aggravated by Long Term Exposure: 路 Individuals sensitive to ester-type local anesthetics (e.g. butacaine, butamben, chloroprocaine, tetracaine, propoxycaine) or to PABA may be hypersensitive to antipyrene and benzocaine. 路 It is not known if Antipyrine and Benzocaine Otic Solution can cause fetal harm or impair reproductive capacity. This medication should only be given to pregnant women if clearly needed. 路 It is not known if this drug is excreted in human milk, so caution should be exercised when administering this medication. Page 2 of 6 BAUSCH & LOMB Pharmaceuticals Division MSDS: Antipyrine and Benzocaine Otic Solution USP 4. FIRST AID MEASURES Eyes: If not prescribed this medication, rinse immediately with copious amounts of water for at least 20 minutes. Contact a physician. Skin: Remove all contaminated clothing and wash skin with copious amounts of water for at least 20 minutes. Contact physician if skin becomes irritated. Ingestion: Wash out mouth and give plenty of water and bland fluids. Seek professional assistance. Inhalation: Remove person to fresh air, and if breathing stops, use artificial respiration. Contact physician immediately. Note to Physicians: None 5. FIRE FIGHTING MEASURES Flammable Properties: Flash point: NE Method: NE Hazardous Products: Toxic Fumes and acrolein. Extinguishing Media: Dry chemical, carbon dioxide, halon, water spray or fog, and foam on surrounding materials. Fire Fighting Instructions: Wear self-contained breathing apparatus and protective clothing. Use water spray to keep fire-exposed containers cool. Do not spray water into the bu...
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  • MSDS PAGE: CAS 60-80-0 94-09-7 134-31-6 56-81-5 MSDS perrigo_com---45802-311_MSDS.asp
    60-80-0 94-09-7 134-31-6 56-81-5 File Name : perrigo_com---45802-311_MSDS.asp Material Safety Data Sheet U.S. Department of Labor May be used to comply with Occupational Safety and Health Administration OSHA鈥檚 Hazard Communication Standard, (Non-Mandatory Form) 29 CFR 1910.1200. Standard must be Form Approved consulted for specific requirements. OMB No. Identity: A/B OTIC DROPS Product Number: D311C Section I Emergency Number Manufacturer鈥檚 Name: 718-960-9978 Clay Park Labs, Inc. Address: General Information 1700 Bathgate Avenue Shabbir Barot: Bronx, NY 10457-5000 718-960-9943 Date Prepared: 05/09/03 Signature of Preparer (optional): Section II 鈥? Hazardous Ingredients/Identity Information Ingredient: ANTIPYRINE USP Ingredient Sequence Number: 01 CAS Number: 60-80-0 ------------------------------------------------------------------- Ingredient: BENZOCAINE USP Ingredient Sequence Number: 02 CAS Number: 94-09-7 ------------------------------------------------------------------- Ingredient: OXYUINOLINE SULFATE Ingredient Sequence Number: 03 CAS Number: 134-31-6 -------------------------------------------------------------------- Ingredient: GLYCERINE 99.5% USP Ingredient Sequence Number: 04 CAS Number: 56-81-5 ------------------------------------------------------------------- Section III 鈥? Physical/Chemical Characteristics Boiling Point: N/A Specific Gravity (H2O = 1): APPROX. 1 Vapor Pressure (mm Hg 20掳C): N/A Melting Point: N/A Vapor Density (AIR = 1): N/A Evaporation Rate: N/A (Diethyl Ether = 1) Solubility in Water: N/A Appearance and Odor: THICK, LIGHT YELLOY, VISCOUS LIQUID, NO ODOR. D311C - AB Otic Drops Page 1 of 3 Section IV 鈥? Fire and Explosion Hazard Data Flash Point: >200掳F Flammable Limits: N/A Extinguishing Media: WATER, CO2, FOAM, DRY CHEMICAL Special Fire Fighting Procedures: N/A Unusual Fire and Explosion Hazards: NONE KNOWN Section V 鈥? Reactivity Data Stability: YES Conditions/Materials to Avoid: STRONG OXIDIZERS Hazardous Decomp Products: BURNING MAY PRODUCE CARBON MONOXIDE AND CARBON DIOXIDE Hazardous Poly Occur: NO Section VI 鈥? Health Hazard Data Route(s) of Entry: Inhalation? NO Skin? NO Ingestion? NO Health Hazards (Acute and Chronic): Eyes: NON-IRRITATING Skin: NON-IRRITATING Inhalation: BURNING, STINGING, OR INCREASED NASAL DISCHARGE Ingestion: MODERATELY TOXIC; NAUSEA, VOMITING, INCOORDINATION,COLDNESS, NUMBNESS OF ARMS AND LEGS. Carcinogenicity: NTP? NO IARC? NO OSHA? NO Signs and Symptoms of Exposure: N/A Medical Conditions Generally Aggravated by Exposure: N/A Emergency/First Aid Procedures: EYES: FLUSH IMMEDIATELY WITH LARGE AMMOUNTS OF WATER FOR AT LEAST 15 MINUTES. IF REDNESS OR IRRITATION PERSISTS, CONTACT A DOCTOR. INGESTION: . CONTACT A DOCTOR IMMEDIATELY. NEVER GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON. INHALATION: SEEK MEDICAL ATTENTION REMOVE TO FRESH AIR. SUPPORT BREATHING (GIVE OXYGEN OR ARTIFICAL RESPIRATION) SKIN: FLUSH WITH MILD SOAD AND WATER. IF IRRITATION PERSISTS, CONTACT A DOCTOR. Section VII 鈥? Precautions for Safe Handling and Use Steps if Released/Spilled: PREVENT BULK LIQUID FROM ENTERING SEWERS OR WATER COURSES. ABSORB LIQUID WITH A SUITABLE ABSORBENT AND DISPOSE OF PROPERLY. Waste Disposal Method: DISPOSE OF IAW/FEDERAL, STATE, AND LOCAL REGULATIONS Precautions-Handling/Storage: NO SPECIAL INSTRUCTIONS Section VIII 鈥? Control Measures Respiratory Protection: N/A Ventilation: N/A Protective Gloves: N/A Eye Protection: N/A D311C - AB Otic Drops Page 2 of 3 Other Protective Clothing or Equipment: N/A Work/Hygiene Practices: N/A DISCLAIMER OF LIABILITY As the conditions or methods of use are beyond our control, we do not assume any responsibility and expressly disclaim any liability for any use of this material. Information contained herein is believed to be true and accurate but all statements or suggestions are made without warranty, express or implied, regarding accuracy of the information, the hazards connected with the use of the material or the results to be obt...
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    ALL PAGES On Chemical Properties IN THIS GROUP
    NameCASSynonymsMolecular FormulaMolecular Weight
    Oleate, sodium 143-19-1 sodium octadec-9-enoateC18H35O2Na306.253
    Oltipraz 64224-21-1 4-methyl-5-pyrazin-2-yl-3H-1,2-dithiole-3-thioneC8H6N2S3225.969
    Omeprazole 73590-58-6 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazoleC17H19N3O3S343.099
    C.I. acid orange 3 6373-74-6 sodium 2-anilino-5-[(2,4-dinitrophenyl)amino]benzenesulfonateC18H15N4O7SNa450.025
    C.I. acid orange 10 1936-15-8 disodium 7-hydroxy-8-[phenyldiazenyl]naphthalene-1,3-disulfonateC16H14N2O7S2Na2447.941
    Orotic acid, monosodium salt 154-85-8 sodium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylateC5H5N2O4Na180.015
    Oxazepam 604-75-1 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-oneC15H11N2O2Cl286.051
    N-(9-Oxo-2-fluorenyl)acetamide 3096-50-2 N-(9-oxo-9H-fluoren-2-yl)acetamideC15H11NO2237.079
    Oxolinic acid 14698-29-4 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acidC13H11NO5261.064
    1-(2-Oxopropyl)nitroso-3-(2-chloroethyl) urea 110559-85-8 N'-(2-chloroethyl)-N-nitroso-N-(2-oxopropyl)ureaC6H10N3O3Cl207.041
    1'-Oxosafrole 30418-53-2 3-(1,3-benzodioxol-5-yl)prop-1-en-1-oneC10H8O3176.047
    Oxprenolol.HCl 6452-73-9 1-[2-(allyloxy)phenoxy]-3-(isopropylamino)propan-2-ol hydrochlorideC15HNO3Cl277.964
    N-Oxydiethylene thiocarbamyl- N-oxydiethylene sulfenamide 13752-51-7 4-[(morpholin-4-ylcarbonothioyl)thio]morpholineC9H16N2O2S2248.065
    N-Oxydiethylenebenzothiazole-2-sulfenamide 102-77-2 2-(morpholin-4-ylthio)-1,3-benzothiazoleC11H12N2OS2252.039
    Oxytetracycline.HCl 2058-46-0 (4S,5R,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochlorideC22HN2O9Cl471.937
    Ozone 10028-15-6 trioxid-2-en-2-ium-1-ideO347.985
    Parathion 56-38-2 O,O-diethyl O-(4-nitrophenyl) thiophosphateC10H14NO5SP289.017
    Patulin 149-29-1 4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-oneC7H6O4154.027
    Penicillin VK 132-98-9 potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylateC16H17N2O5SK388.049
    Pentachloroanisole 1825-21-4 1,2,3,4,5-pentachloro-6-methoxybenzeneC7H3OCl5277.863
    Pentachloronitrobenzene 82-68-8 1,2,3,4,5-pentachloro-6-nitrobenzeneC6NO2Cl5292.837
    Pentanal methylformylhydrazone 57590-20-2 N-methyl-N'-[(1E)-pentylidene]formic hydrazideC7H14N2O142.111
    N-Pentyl-N'-nitro-N-nitrosoguanidine 13010-10-1 N'-nitro-N-nitroso-N-pentylguanidineC6H13N5O3203.102
    n-Pentylhydrazine.HCl 1119-68-2 pentylhydrazine hydrochlorideC5HN2Cl123.983
    Perhexiline maleate 6724-53-4 Piperidine, 2-(2,2-dicyclohexylethyl)-, 2-butenedioate (1:1)C23H2NO4355.998
    Petasitenine 60102-37-6 (11Z)-7-hydroxy-3',6,7,14-tetramethyl-8H,17H-spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trioneC19H27NO7381.179
    Phenacetin 62-44-2 N-(4-ethoxyphenyl)acetamideC10H13NO2179.095
    Phenazone 60-80-0 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-oneC11H12N2O188.095
    Phenazopyridine.HCl 136-40-3 3-[phenyldiazenyl]pyridine-2,6-diamine hydrochlorideC11HN5Cl237.992
    Phenesterin 3546-10-9 cholest-5-en-3-yl {4-[bis(2-chloroethyl)amino]phenyl}acetateC39H59NO2Cl2643.392
    Phenethyl isothiocyanate 2257-09-2 (2-isothiocyanatoethyl)benzeneC9H9NS163.046
    Phenformin.HCl 834-28-6 N-(2-phenylethyl)imidodicarbonimidic diamide hydrochlorideC10HN5Cl225.992
    Phenobarbital, sodium 57-30-7 sodium 5-ethyl-4,6-dioxo-5-phenyl-1,4,5,6-tetrahydropyrimidin-2-olateC12H13N2O3Na256.082
    Phenothiazine 92-84-2 10H-phenothiazineC12H9NS199.046
    Phenoxybenzamine.HCl 63-92-3 N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine hydrochlorideC18HNOCl2316.944
    1-Phenyl-3,3-dimethyltriazene 7227-91-0 3,3-dimethyl-1-phenyltriaz-1-eneC8H11N3149.095
    Phenyl isothiocyanate 103-72-0 isothiocyanatobenzeneC7H5NS135.014
    1-Phenyl-3-methyl-5-pyrazolone 89-25-8 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-oneC10H10N2O174.079
    N-Phenyl-p-phenylenediamine.HCl 2198-59-6 N-phenylbenzene-1,4-diamine hydrochlorideC12HN2Cl207.983
    (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid 89667-40-3 (6E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acidC18H19NO2281.142
    1-Phenyl-2-thiourea 103-85-5 N-phenylthioureaC7H8N2S152.041
    1-Phenylazo-2-naphthol 842-07-9 1-[phenyldiazenyl]-2-naphtholC16H12N2O248.095
    Phenylbutazone 50-33-9 4-butyl-1,2-diphenylpyrazolidine-3,5-dioneC19H20N2O2308.153
    p-Phenylenediamine 106-50-3 benzene-1,4-diamineC6H8N2108.069
    m-Phenylenediamine.2HCl 541-69-5 benzene-1,3-diamine dihydrochlorideC6H2N2Cl2171.96
    o-Phenylenediamine.2HCl 615-28-1 benzene-1,2-diamine dihydrochlorideC6H2N2Cl2171.96
    p-Phenylenediamine.2HCl 624-18-0 benzene-1,4-diamine dihydrochlorideC6H2N2Cl2171.96
    Phenylephrine.HCl 61-76-7 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol hydrochlorideC9HNO2Cl189.97
    Phenylethyl-3-methylcaffeate 71835-85-3 2-Phenylethyl 3-(4-hydroxy-3-methoxyphenyl)-2-propenoateC18H18O4298.12
    Phenylethylhydrazine sulfate 156-51-4 (2-phenylethyl)hydrazine sulfateC8H14N2O4S230.036

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